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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 347197Generated: October 30, 2026

Propylamine → {4-[2-Methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophen-6-yloxy]-butyl]-propyl-amine

https://huagongshe.com/reaction/347197

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropylamineHCID 7852—
Reactant6-(4-Bromo-butoxy)-2-methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiopheneHCID 22314148—
Product{4-[2-Methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophen-6-yloxy]-butyl]-propyl-amineHCID 22313949—

Reaction Steps

According to the method in example 31, 6-(4-Bromo-butoxy)-2-methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophene and N-propyl amine were converted to yield {4-[2-Methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-propyl-amine as yellowish oil, MS: 422 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07173043B2
Source datasetuspto-grants-2007_02
ORD IDord-23e87232600a459c8ef6c2c30436fcf7
Source noteuspto-grants-2007_02