HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-dihydro-2H-pyran → 21-Tetrahydropyranyl-16alpha-cyano-11beta-hydroxy-3,20-dioxo-1,4-pregnadiene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| Reactant | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| Reactant | 16alpha-Cyano-11beta,21-dihydroxy-3,20-dioxo-1,4-pregnadiene | HCID 14233405 | — |
| Product | 21-Tetrahydropyranyl-16alpha-cyano-11beta-hydroxy-3,20-dioxo-1,4-pregnadiene | HCID 22839304 | — |
Reaction Steps
The process of claim 9 which additionally comprises reacting (VI) with 2,3-dihydropyran and pyridinium tosylate to produce (VII) 21-tetrahydropyranyl-16α-cyano-11β-hydroxy-3,20-dioxo-1,4-pregnadiene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04762919 |
| Source dataset | uspto-grants-1988_08 |
| ORD ID | ord-03b553c320894322b5171b838209cce9 |
| Source note | uspto-grants-1988_08 |