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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 347279Generated: October 29, 2026

2-Chlorobenzothiazole → 2-(s)-(Benzothiazol-2-ylamino)-3-cyclohexyl-n-[2-(4-methoxy-phenylamino)-ethyl]-propionamide

https://huagongshe.com/reaction/347279

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChlorobenzothiazoleHCID 11987—
Reactant3-Cyclohexyl-L-alanineHCID 712421—
ReactantN~1~-(4-Methoxyphenyl)ethane-1,2-diamineHCID 12666396—
Product2-(s)-(Benzothiazol-2-ylamino)-3-cyclohexyl-n-[2-(4-methoxy-phenylamino)-ethyl]-propionamideHCID 11305523—

Reaction Steps

The title compound was prepared from 2-chlorobenzothiazole, L-cyclohexylalanine and N1-(4-methoxy-phenyl)-ethane-1,2-diamine.2HCl using the procedure analogous to that described in example 2. HPLC-MS calcd. for C25H32N4O2S (M+H+) 453.22. found 453.5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07173051B2
Source datasetuspto-grants-2007_02
ORD IDord-259a22cd99e54ec49c0d43815112853e
Source noteuspto-grants-2007_02