HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyclohexyl-L-alanine → methyl 2-{[(1S)-2-cyclohexyl-1-({2-[(4-fluorophenyl)amino]ethyl}carbamoyl)ethyl]amino}-1,3-benzoxazole-6-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyclohexyl-L-alanine | HCID 712421 | — |
| Reactant | N-(4-Fluorophenyl)ethylenediamine | HCID 3016534 | — |
| Reactant | Methyl 2-chloro-1,3-benzoxazole-6-carboxylate | HCID 58433755 | — |
| Product | methyl 2-{[(1S)-2-cyclohexyl-1-({2-[(4-fluorophenyl)amino]ethyl}carbamoyl)ethyl]amino}-1,3-benzoxazole-6-carboxylate | HCID 11397519 | — |
Reaction Steps
The title compound was prepared from 2-Chloro-benzooxazole-6-carboxylic acid methyl ester, L-cyclohexylalanine and N1-(4-fluoro-phenyl)-ethane-1,2-diamine.2HCl using the procedure analogous to that described in example 2. HPLC-MS calcd. for C26H31FN4O4 (M+H+)483.23. found 483.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07173051B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-0f4d58bb380041859f3679f138f56c41 |
| Source note | uspto-grants-2007_02 |