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HRID347309

反应详情

EQUATION

反应方程式

HRID 347309 的结构方程式

REACTANTS

反应物

2
结构：O=[N+]([O-])/C=C/c1ccc(F)cc1
HCID5381680

1-Fluoro-4-[(1E)-2-nitroethenyl]benzene

C8H6FNO2

结构：CCOC(=O)C1CCN([C@@H]2CCCC[C@@H]2c2ccc(F)cc2)CC1
HCID66918204

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)C1(C(C[N+](=O)[O-])c2ccc(F)cc2)CCN([C@@H]2CCCC[C@@H]2c2ccc(F)cc2)CC1
HCID66918273

未命名化合物

收率 77%

PROCEDURE

实验过程

As described for example 1b, cis-rac-1-[2-(4-fluoro-phenyl)-cyclohexyl]-piperidine-4-carboxylic acid ethyl ester (1.0 g, 3 mmol) (using 4-fluoro-trans-beta-nitrostyrene instead of trans-beta-nitrostyrene) was converted to the title compound (1.2 g, 77%) which was obtained as a white solid. MS: m/e=501.4 (M+H).