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HRID347310

反应详情

EQUATION

反应方程式

HRID 347310 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(C=C[N+](=O)[O-])cc1
HCID229843

未命名化合物

结构：CCOC(=O)C1CCN([C@@H]2CCCC[C@@H]2c2ccc(F)cc2)CC1
HCID66918204

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(C2CNC(=O)C23CCN([C@@H]2CCCC[C@@H]2c2ccc(F)cc2)CC3)cc1
HCID131726234

未命名化合物

收率 52%

PROCEDURE

实验过程

As described for example 1b, cis-rac-1-[2-(4-fluoro-phenyl)-cyclohexyl]-piperidine-4-carboxylic acid ethyl ester (800 mg, 2.4 mmol) (using 4-methoxy-beta-nitrostyrene instead of trans-beta-nitrostyrene) was converted to the title compound (642 mg) 52%) which was obtained as a light yellow foam. MS: m/e=513.4 (M+H).