2-Chloro-3,5-dinitropyridine → HCID 21082864, compound

HRID 347586Notes

Reaction equation

[Cl:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][C:5]([N+:11]([O-])=O)=[CH:4][N:3]=1.[OH:14][CH:15]1[CH2:19][CH2:18][NH:17][CH2:16]1>>[ClH:1].[ClH:1].[NH2:8][C:7]1[C:2]([N:17]2[CH2:18][CH2:19][CH:15]([OH:14])[CH2:16]2)=[N:3][CH:4]=[C:5]([NH2:11])[CH:6]=1

Participants

Reactant 2

HCID 757382-Chloro-3,5-dinitropyridine

HCID 982104-Hydroxypyrrolidine

Product 1

HCID 21082864HCID 21082864, compound

Procedure

2 g (0.01 mol) of 3,5-dinitro-2-(3-hydroxypyrrolidin-1-yl)pyridine obtained according to Protocol A from 2-chloro-3,5-dinitropyridine and 3-hydroxypyrrolidine, were reduced according to Protocol B, to give 1.1 g of N-(3,5-diaminopyrid-2-yl)-3-hydroxypyrrolidine dihydrochloride.

Sources & evidence

ORD record: ord-706ea7c8655346b48daa5c6b9d612733
Source dataset: uspto-grants-2007_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07175670B2

Reaction notes

Loading…