反应详情

The carboxylic acid from Example C (0.31 g, 1.93 mmol) was reacted with 1-(3-pyridyl)methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine from Example 16A (0.39 g, 1.61 mmol) according to the procedure in Example 1A. The product was purified by flash chromatography on silica (eluant EtOAc); yield 0.28 g (45%).

1. customThe product was purified by flash chromatography on silica (eluant EtOAc)