HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyano-3-methylbenzoic acid → 4-(4-Cyano-3-methylbenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyano-3-methylbenzoic acid | HCID 10241099 | — |
| Reactant | 5,6,7,8-Tetrahydro-4H-thieno[3,2-B]azepine | HCID 11804971 | — |
| Product | 4-(4-Cyano-3-methylbenzoyl)-5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine | HCID 21083265 | — |
Reaction Steps
The carboxylic acid from Example C (0.50 g, 3.10 mmol) was reacted with 5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine (0.45 g, 2.95 mmol) according to the procedure in Example 1A. The product was purified by recrystallisation from EtOAc:pet. ether; yield 0.48 g (55%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07176195B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-53083ddc49594f02bd27d04984cc2e63 |
| Source note | uspto-grants-2007_02 |