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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 347710Generated: October 25, 2026

2-Thiopheneglyoxylic acid → 6-Hydroxymethyl-3-thiophen-2-yl-1H-quinoxalin-2-one

https://huagongshe.com/reaction/347710

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneglyoxylic acidHCID 77694—
Reactant(3,4-Diaminophenyl)methanolHCID 12902832—
Product6-Hydroxymethyl-3-thiophen-2-yl-1H-quinoxalin-2-oneHCID 21083665—

Reaction Steps

The quinoxalin-2-one of the present example is prepared with (3,4-Diamino-phenyl)-methanol and (thiophen-2-yl) oxo-acetic acid via the method described in Example 12 to afford 6-Hydroxymethyl-3-thiophen-2-yl-1H-quinoxalin-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07176208B2
Source datasetuspto-grants-2007_02
ORD IDord-ce2ba019a927490db425dca9e72b9fef
Source noteuspto-grants-2007_02