反应详情

温度

130 °C

5 g of 2-amino-3-cyano-4-chloroquinolin and 11 ml of benzylamine are heated under stirring at 130° C. The reaction mixture is poured onto 50 ml of water, the resulting precipitate is filtered off, washed with 50 ml of water. The pale-yellow precipitate is recrystallized from dimethylformamide to obtain 5.2 g of the title compound. Mp.: 206° C.

1. filtrationthe resulting precipitate is filtered off
2. washwashed with 50 ml of water
3. customThe pale-yellow precipitate is recrystallized from dimethylformamide