HCID 10535139, compound → Ethyl 2-azabicyclo[2.2.2]octane-3-carboxylate
Reaction equation
C1(C([N:9]2[CH:14]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:13]3[CH2:20][CH2:21][CH:10]2[CH:11]=[CH:12]3)C)C=CC=CC=1.[C@@H]12C[C@@H](CC1)[C@H](C(OCC)=O)N2>>[CH:10]12[CH2:11][CH2:12][CH:13]([CH2:20][CH2:21]1)[CH:14]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[NH:9]2Participants
3
Procedure
Ethyl 2-(1-phenylethyl)-2-azabicyclo[2.2.2]oct-5-ene-3-carboxylate is subjected to a reaction similar to the reaction (b) of Example 1, to give ethyl 2-azabicyclo[2.2.2]octane-3-carboxylate.
Sources & evidence
- ORD record
- ord-99aa85cb80904c5d94108027dbe3444e
- Source dataset
- uspto-grants-2007_02
- Patent number
- US07176217B2
Reaction notes
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