HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 1,5-Diacetyl-2-indolinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 5-acetyl-2,3-dihydro-1H-indol-2-one | HCID 10219643 | — |
| Product | 1,5-Diacetyl-2-indolinone | HCID 21084560 | — |
Reaction Steps
48.9 g (0.279 mol) 5-acetyl-2-indolinone are stirred in 400 ml acetic anhydride in an oil bath at 140° C. for 2 h. During this time the starting material dissolves. Then the reaction mixture is left to cool, evaporated down, the precipitate is removed by suction filtering, washed with ether and the product is dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07176231B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-dd569b4deb3f4ef7aa753519503f42f0 |
| Source note | uspto-grants-2007_02 |