Acetic Anhydride → 1-Acetyl-5-benzoyl-2-indolinone

HRID 347950Notes

Reaction equation

[C:1]([C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][C:13](=[O:18])[CH2:12]2)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:19](OC(=O)C)(=[O:21])[CH3:20]>>[C:19]([N:14]1[C:15]2[C:11](=[CH:10][C:9]([C:1](=[O:8])[C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)=[CH:17][CH:16]=2)[CH2:12][C:13]1=[O:18])(=[O:21])[CH3:20]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 134081645-Benzoyl-1,3-dihydro-2H-indol-2-one

Product 1

HCID 210846311-Acetyl-5-benzoyl-2-indolinone

Procedure

Prepared from 5-benzoyl-2-indolinone and acetic anhydride

Sources & evidence

ORD record: ord-623bb6c1eb4645609e3e4ede491584f2
Source dataset: uspto-grants-2007_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07176231B2

Reaction notes

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