Acetic Anhydride → 1-Acetyl-5-butyryl-3-(ethoxy-phenyl-methylidene)-2-indolinone

Participants

Reaction Conditions

Reaction Steps

10 g (49 mmol) 5-butyryl-2-indolinone (Ex. I.2) in 200 ml acetic anhydride are stirred for 5 h at 130° C. Then 35 ml triethyl orthobenzoate are added and the mixture is stirred for a further 4 h at 100° C. It is then evaporated down and the resulting precipitate is suction filtered, washed and dried.

Provenance & Evidence