Acetic Anhydride → HCID 68993257, compound

HRID 347962Notes

Reaction equation

HRID 347962 reaction equation
[C:1]([C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[NH:9][C:8](=[O:13])[CH2:7]2)(=[O:3])[CH3:2].[C:14]([O:17][C:18](=O)[CH3:19])(=O)C.[C:21](OC)(OC)([O:23]C)[CH3:22]>C(Cl)Cl.CO>[C:21]([N:9]1[C:10]2[C:6](=[CH:5][C:4]([C:1](=[O:3])[CH3:2])=[CH:12][CH:11]=2)[C:7](=[C:18]([O:17][CH3:14])[CH3:19])[C:8]1=[O:13])(=[O:23])[CH3:22]

Participants

5

Reactant 3

HCID 7918Acetic AnhydrideHCID 15050Trimethyl orthoacetateHCID 102196435-acetyl-2,3-dihydro-1H-indol-2-one

Product 1

HCID 68993257HCID 68993257, compound

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent

Procedure

Prepared from 5-acetyl-2-indolinone, acetic anhydride and trimethyl orthoacetate Rf=0.40 (silica gel, methylene chloride/methanol 50:1)

Sources & evidence

ORD record
ord-3beddc05a0c74074b44b95d0e71e348d
Source dataset
uspto-grants-2007_02
Patent number
US07176231B2

Reaction notes

Loading…