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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 3482Generated: October 26, 2026

Pyridine-2-acetonitrile → 6-Pyridin-2-yl-pyrido[2,3-d]pyrimidine-2,7-diamine

https://huagongshe.com/reaction/3482

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridine-2-acetonitrileHCID 75959—
Reactant2,4-Diaminopyrimidine-5-carbaldehydeHCID 309176—
Product6-Pyridin-2-yl-pyrido[2,3-d]pyrimidine-2,7-diamineHCID 21850058—

Reaction Steps

The procedure of Example 1 was followed to react 0.84 mL of 2-pyridylacetonitrile and 1.0 g of 2,4-diamino-5-pyrimidinecarboxaldehyde to afford the title compound, mp 312°-321° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05733913
Source datasetuspto-grants-1998_03
ORD IDord-1d437903b7d7465cbd657fadc7a517dd
Source noteuspto-grants-1998_03