Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(4-Benzyloxy-3-methoxyphenyl)-2-methyl-2-phenoxypropionic Acid → 3-(4-Hydroxy-3-methoxy-phenyl)-2-methyl-2-phenoxypropionic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(4-Benzyloxy-3-methoxyphenyl)-2-methyl-2-phenoxypropionic Acid | HCID 22339970 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-(4-Hydroxy-3-methoxy-phenyl)-2-methyl-2-phenoxypropionic Acid | HCID 22339982 | — |
반응 단계
A solution of 3-(4-benzyloxy-3-methoxyphenyl)-2-methyl-2-phenoxypropionic acid (6.86 g, 17.5 mmol) in EtOH (175 mL) was added to 5% Pd/C (186 mg, 10 wt %). The mixture was purged first with nitrogen, then with H2, which was then applied at 45 p.s.i. for 2 h. Pd/C was subsequently filtered off through celite, and the filtrate was concentrated to a crude oil (5.42 g, in excess of theory). MS (EI) 301.2 (M−H)−.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07176224B2 |
| 출처 데이터셋 | uspto-grants-2007_02 |
| ORD ID | ord-a91a9e5bcb3e461a9bcc70bfa790c554 |
| 출처 메모 | uspto-grants-2007_02 |