HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 69523377, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid | HCID 21087356 | — |
| Reactant | HCID 54685033 | HCID 54685033 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 69523377 | HCID 69523377 | 15% |
Reaction Steps
The titled compound was prepared from [5-(4-fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid using 3-hydroxy-5-methoxy-1-methyl-1H-indole-2-carboxylic acid methyl ester (40 mg, 0.17 mmol) as the source alcohol. Chromatography (1:1 ethyl acetate:hexane) through SiO2 yielded 13 mg (15%) of the titled compound. ESI-MS m/z 509 (MH+), 507 (M−H−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07176310B1 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-c40ea1ecb44746a4bfbd1054093a4133 |
| Source note | uspto-grants-2007_02 |