HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 69523255, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Cyclopropanemethanol | HCID 75644 | — |
| Reactant | [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid | HCID 21087356 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 69523255 | HCID 69523255 | 83% |
Reaction Steps
The titled compound was prepared from [5-(4-fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid using cyclopropanemethanol (28 μL, 0.34 mmol) as the coupling partner. Chromatography (1: 1 methanol:dichloromethane) through SiO2 yielded 49 mg (83%) of the titled compound as a white solid. ESI-MS m/z 346 (MH+), 344 (M−H−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07176310B1 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-62e5fa310d1446b0b98afd18d8ba7147 |
| Source note | uspto-grants-2007_02 |