HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cycloheptanol → [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid cycloheptyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cycloheptanol | HCID 10399 | — |
| Reactant | [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid | HCID 21087356 | — |
| Product | [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid cycloheptyl ester | HCID 69522980 | 80% |
Reaction Steps
The titled compound was prepared from [5-(4-fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid using cycloheptanol (39 mg, 0.34 mmol) as the coupling partner. Concentration (no chromatography) yielded 53 mg (80%) of the titled compound. ESI-MS m/z 388 (MH+), 386 (M−H−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07176310B1 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-0142e648bbdc430eba2ca83f12ea6a37 |
| Source note | uspto-grants-2007_02 |