HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitroaniline → HCID 86760392, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitroaniline | HCID 7475 | — |
| Reactant | [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid | HCID 21087356 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 86760392 | HCID 86760392 | 23% |
Reaction Steps
The titled compound was prepared from [5-(4-fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid using 4-nitroaniline (25 mg, 0.18 mmol) as the coupling partner. Chromatography (5% methanol/dichloromethane) through SiO2 yielded 13 mg (23%) of the titled compound. ESI-MS m/z 412 (MH+), 410 (M−H−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07176310B1 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-0766cc1d19194a8998db88e3f280213c |
| Source note | uspto-grants-2007_02 |