HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethyl Acetate → HCID 86760394, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethyl Acetate | HCID 8857 | — |
| Edukt | 3-Amino-N-butylbenzenesulfonamide | HCID 5137973 | — |
| Edukt | [5-(4-Fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid | HCID 21087356 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | HCID 86760394 | HCID 86760394 | 27% |
Reaktionsschritte
The titled compound was prepared from [5-(4-fluorophenylcarbamoyl)pyrimidin-2-yloxy]acetic acid using 3-amino-N-butyl-benzenesulfonamide (53 mg, 0.21 mmol) as the coupling partner. Chromatography (1:1 ethyl acetate:dichloromethane) through SiO2 yielded 23 mg (27%) of the titled compound. ESI-MS m/z 502 (MH+), 500 (M−H−).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07176310B1 |
| Quelldatensatz | uspto-grants-2007_02 |
| ORD ID | ord-c61610a7835242e8bdb1272920cfc583 |
| Quellennotiz | uspto-grants-2007_02 |