m-Chloroperbenzoic acid → HCID 86760398, compound

Participants

Reaction Steps

A solution of 2-carbamoylmethylsulfanyl-4-methylpyrimidine-5-carboxylic acid (4-fluorophenyl)amide (77 mg, 0.24 mmol) and m-CPBA (64 mg, 0.37 mmol) in 2 mL of dichloromethane was stirred at ambient temperature for 16 h. The reaction was concentrated in vacuo and chromatographed through SiO2 (5–10% methanol/dichloromethane), to afford 53 mg (66% yield) of the titled product. ApcI-MS m/z 337 (MH+).

Provenance & Evidence