HCID 43811255, compound → Ethyl 6-methoxy-9H-carbazole-3-carboxylate

Participants

Reaction Conditions

Reaction Steps

A solution of 6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid ethyl ester (3.29 g, 12.1 mmol) in p-cymene (12 mL) was treated with palladium (10% on carbon, 2.25 g) and heated at 190° C. for 20 hours. The mixture was then cooled, diluted with dichloromethane and filtered over a pad of diatomaceous earth. The filtrate was concentrated in vacuo to a low volume and heptane (200 mL) was added to precipitate the title compound as a white solid (2.78 g).

Provenance & Evidence