化工社化工社 化学情報印刷レポート · 研究参考用
(1-methyl-1H-benzo[d]imidazol-5-yl)methanol → 1-methyl-1H-1,3-benzodiazole-5-carbaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (1-methyl-1H-benzo[d]imidazol-5-yl)methanol | HCID 14518388 | — |
| 触媒 | Manganese dioxide | HCID 14801 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 1-methyl-1H-1,3-benzodiazole-5-carbaldehyde | HCID 17904497 | 98.3% |
反応手順
A solution of 5-hydroxymethyl-1-methylbenzimidazole (0.8 g, 4 mmol) in acetone (40 mL) was treated with MnO2 (4 g) and the mixture was stirred for 3 days. The solid was filtered off and the solvent removed under reduced pressure to give 0.63 g of product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07176322B2 |
| 出典データセット | uspto-grants-2007_02 |
| ORD ID | ord-9d49901caf964372b699c655bec9b8db |
| 出典メモ | uspto-grants-2007_02 |