反应详情

The compound (70.0 mg) obtained in Example 25-3 was added with a 40% methylamine/methanol solution (3.0 ml) and then stirred at room temperature for 14 hours. After completion of the reaction, the solvent was distilled off. Then, the residue was then added with a 1 mol/l sodium hydroxide aqueous solution and chloroform to extract the aqueous layer therefrom with chloroform. The extract was dried with anhydrous sodium sulfate, and the solvent was distilled off, thereby obtaining the subject compound (65.5 mg) as a colorless viscous liquid.

1. customAfter completion of the reaction
2. distillationthe solvent was distilled off
3. additionThen, the residue was then added with a 1 mol/l sodium hydroxide aqueous solution and chloroform
4. extractionto extract the aqueous layer
5. dry with materialThe extract was dried with anhydrous sodium sulfate
6. distillationthe solvent was distilled off