3,5-Dimethyl-2-hydroxymethyl-4-methoxy-pyridine → 4-Methoxy-3,5-dimethylpyridine-2-carbaldehyde

Participants

Reaction Steps

(4-methoxy-3,5-dimethyl-pyridin-2-yl)methanol (Tokyo Kasei Kogyo Co., Ltd.) (300 mg) was dissolved in chloroform (15 ml) and added with manganese dioxide (chemically processed product) (3.00 g), followed by stirring for 3 hours. After completion of the reaction, the solution was filtrated through Celite and the solvent was then distilled off, thereby obtaining the subject compound (297 mg) as a white solid.

Provenance & Evidence