Spironolactone → Canrenoic acid

HRID 348775Notes

Reaction equation

[CH3:1][C@@:2]12[C@H:12]3[CH2:13][CH2:14][C@:15]4([CH3:25])[C@@:19]5([O:24][C:22](=[O:23])[CH2:21][CH2:20]5)[CH2:18][CH2:17][C@H:16]4[C@@H:11]3[CH:10]=[CH:9][C:8]1=[CH:7][C:5](=[O:6])[CH2:4][CH2:3]2.CC([O:29]C([C@H]1[C@H]2[C@H]3[C@](C)(CC[C@@H]2[C@]2(C)C(=CC(CC2)=O)C1)[C@@]1(OC(=O)CC1)CC3)=O)C.C[C@@]12[C@H]3CC[C@]4(C)[C@](O)(CCC(O)=O)CC[C@H]4[C@@H]3[C@H](C(OC)=O)CC1=CC(=O)CC2.C[C@@]12[C@H]3CC[C@]4(C)[C@](O)(CCC(O)=O)CC[C@H]4[C@@H]3[C@@H]3[C@@H](C3)C1=CC(=O)CC2.CC(S[C@H]1[C@H]2[C@H]3[C@](C)(CC[C@@H]2[C@]2(C)C(=CC(CC2)=O)C1)[C@@]1(OC(=O)CC1)CC3)=O.C[C@@]12[C@](O)(C)CC[C@H]1[C@@H]1CC[C@@]34O[C@]3(C)C(O)=C(C#N)C[C@]4(C)[C@H]1CC2.CC(S[C@H]1[C@H]2[C@H]3[C@](C)(CC[C@@H]2[C@]2(C)C(=CC(C=C2)=O)C1)[C@@]1(OC(=O)CC1)[C@@H]1[C@H]3C1)=O.CCC[C@H]1[C@H]2[C@H]3[C@](C)(CC[C@@H]2[C@]2(C)C(=CC(CC2)=O)C1)[C@](O)(CCC(O)=O)CC3.C[C@@]12[C@@]3(OC(=O)CC3)[C@@H]3[C@@H](C3)[C@H]1[C@@H]1[C@@H]3[C@H](C4[C@@](C)([C@H]1CC2)C=CC(=O)C=4)C3.CC(S[C@H]1[C@H]2[C@H]3[C@](C)(CC[C@@H]2[C@]2(C)C(=CC(CC2)=O)C1)[C@@]1(OCCC1)CC3)=O.C[C@@]12[C@H]3CC[C@]4(C)[C@@]5(OC(=O)CC5)CC[C@H]4[C@@H]3[C@H]3[C@H](C3)C1=CC(=O)CC2.C[C@@]12[C@@]34O[C@@H]3C[C@]3(C)[C@@]5(OC(=O)CC5)CC[C@H]3[C@@H]4[C@H](C(OC)=O)CC1=CC(=O)CC2>>[CH3:1][C@@:2]12[C@H:12]3[CH2:13][CH2:14][C@:15]4([CH3:25])[C@:19]([OH:29])([CH2:20][CH2:21][C:22]([OH:24])=[O:23])[CH2:18][CH2:17][C@H:16]4[C@@H:11]3[CH:10]=[CH:9][C:8]1=[CH:7][C:5](=[O:6])[CH2:4][CH2:3]2