HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Amino-4-(benzyloxy)butan-1-ol Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | tert-Butyl 3-(benzyloxy)-1-(hydroxymethyl)propylcarbamate | HCID 21087273 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-Amino-4-(benzyloxy)butan-1-ol Hydrochloride | HCID 21085424 | — |
Reaction Steps
tert-Butyl 3-(benzyloxy)-1-(hydroxymethyl)propylcarbamate (5 g, 17 mmol) is dissolved in 4 N hydrochloric acid in dioxane (21 mL) and stirred for 3 h at room temperature. The solution is concentrated under reduced pressure to give the title compound in pure form. ESI MS m/z 196.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07176242B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-2b78f1cc2bc24b6a82c3a517d95c8c4e |
| Source note | uspto-grants-2007_02 |