HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trimethylsilyldiazomethane → Methyl 3-bromo-5-(hydroxymethyl)benzoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trimethylsilyldiazomethane | HCID 167693 | — |
| Edukt | 3-Bromo-5-(hydroxymethyl)benzoic acid | HCID 8167127 | — |
| Lösungsmittel | Benzene methanol | HCID 21927730 | — |
| Produkt | Methyl 3-bromo-5-(hydroxymethyl)benzoate | HCID 11356988 | — |
Reaktionsschritte
To 3-bromo-5-(hydroxymethyl)benzoic acid (7.0 g, 30 mmol) in 20% methanol/benzene (100 mL) is added trimethylsilyldiazomethane (2M in hexanes), and the reaction is stirred 16 h. The reaction is concentrated under reduced pressure to afford the title compound. ESI MS m/z 244.0 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07176242B2 |
| Quelldatensatz | uspto-grants-2007_02 |
| ORD ID | ord-2db7ca275b6a4534b129f756e372e808 |
| Quellennotiz | uspto-grants-2007_02 |