HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Cyclohexen-1-one → 1,3-Diethyl 2-(3-oxocyclohexyl)propanedioate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Cyclohexen-1-one | HCID 13594 | — |
| Reactant | 2-(3-Oxo-4-propylcyclohexyl)-malonic acid diethyl ester | HCID 57487436 | — |
| Product | 1,3-Diethyl 2-(3-oxocyclohexyl)propanedioate | HCID 317049 | 88% |
Reaction Steps
Step 1 (3-Oxo-cyclohexyl)-malonic acid diethyl ester was prepared in 88% yield from cyclohexenone by the method described above for the synthesis of 2-(3-oxo-4-propyl-cyclohexyl)-malonic acid diethyl ester: 1H NMR (300 MHz, CDCl3) δ 4.44–4.12 (m, 4H), 2.88–1.22 (m, 16H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07176242B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-051d527bec824cc8a072ae0b5466a09d |
| Source note | uspto-grants-2007_02 |