Sodium Hydroxide → HCID 19851772, compound

HRID 34913Notes

Reaction equation

HRID 34913 reaction equation
Cl.Cl.[N:3]1[CH:8]=[CH:7][CH:6]=[C:5]([CH2:9][C:10]2[CH:11]=[CH:12][C:13](=[O:16])[NH:14][CH:15]=2)[CH:4]=1.[OH-].[Na+]>O>[N:3]1[CH:8]=[CH:7][CH:6]=[C:5]([CH2:9][C:10]2[CH:11]=[CH:12][C:13](=[O:16])[NH:14][CH:15]=2)[CH:4]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 198517715-(3-Pyridylmethyl)-2-pyridone dihydrochloride

Product 1

HCID 19851772HCID 19851772, compoundYield 100.5%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

5-(3-Pyridylmethyl)-2-pyridone dihydrochloride (36 g) was dissolved in water, basified with sodium hydroxide and extracted into chloroform (3×100 ml). The combined extracts were dried over magnesium sulphate and the solvent removed to give 5-(3-pyridylmethyl)-2-pyridone (26 g), m.p. 142°-144° C.

Workup

  1. extractionextracted into chloroform (3×100 ml)
  2. dry with materialThe combined extracts were dried over magnesium sulphate
  3. customthe solvent removed

Sources & evidence

ORD record
ord-9aea2a4936de42c58d7f21fa0b123cff
Source dataset
uspto-grants-1988_08
Patent number
US04764519

Reaction notes

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