Trifluoroacetic acid → 4-(2-Ethoxycarbonyloxy-1-fluoro-ethylidene)-piperidine

Participants

Reaction Steps

4-(1-Chloro-2-propenylidene)piperidine TFA salt (110; Scheme XXIX) To compound 109 (0.1415 g, 0.5489 mmol) in CH2Cl2 (5 mL) was added TFA (0.55 mL, 7.1 mmols) and the mixture stirred for 3 hrs whereupon all volatile materials were removed in vacuo. The crude title compound so obtained was used without further purification. MS 158 (M+H).

Provenance & Evidence