Trifluoroacetic acid → HCID 13800266, compound

Participants

Reaction Steps

12.5 g of t-butyl [2-(4-chloro-3-methylpyridine-2-carboxamido)ethyl]carbamate were reacted with trifluoroacetic acid in an analogous manner to that described in Example 2, paragraph 2. The residue was converted into the hydrochloride which was recrystallized from ethanol/ether, whereby there was obtained N-(2-aminoethyl)-4-chloro-3-methylpyridine-2-carboxamide hydrochloride as white crystals, m.p. 180°-181°.

Provenance & Evidence