HCID 69819494, compound → HCID 17962032, compound

Participants

Reaction Steps

A solution of ethyl (E)-3-(1-methyl-5-triphenylmethylaminopyrazol-4-yl)acrylate (60 g, 137 mmol) in ethanol (700 ml) was treated with 10% palladium carbon (6.0 g) under a hydrogen atmosphere at room temperature for 3 hours. After the catalyst was filtered off, the filtrate was concentrated in vacuo. The residue was triturated with hexane and dried in vacuo to give ethyl 3-(1-methyl-5-triphenylmethylaminopyrazol-4-yl)propionate (63 g) as a colorless solid.

Provenance & Evidence