HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 349534Generated: October 30, 2026
Ethyl formate → N-{5-amino-1-[2-(trityloxy)ethyl]pyrazol-4-yl}methylformamide
https://huagongshe.com/reaction/349534
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl formate | HCID 8025 | — |
| Reactant | {5-Amino-1-[2-(trityloxy)ethyl]pyrazol-4-yl}methylamine | HCID 17961999 | — |
| Product | N-{5-amino-1-[2-(trityloxy)ethyl]pyrazol-4-yl}methylformamide | HCID 17961970 | — |
Reaction Steps
A suspension of {5-amino-1-[2-(trityloxy)ethyl]pyrazol-4-yl}methylamine (19.7 g, 49.4 mmol) in ethyl formate (500 ml) was stirred at 50° C. for 3 hours. After evaporation of the solvent in vacuo, the residue was triturated with diisopropyl ether to give N-{5-amino-1-[2-(trityloxy)ethyl]pyrazol-4-yl}methylformamide (7.99 g) as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07179801B2 |
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| Source dataset | uspto-grants-2007_02 |
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| ORD ID | ord-4c9b6b36a895442d9ca5ab9940a10219 |
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| Source note | uspto-grants-2007_02 |
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