HuagongsheHuagongshe Chemistry Print Report · For research reference only
8alpha-Benzyloxycarbonylamino-6-n-propylergoline → 8alpha-Amino-6-n-propylergoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8alpha-Benzyloxycarbonylamino-6-n-propylergoline | HCID 13966458 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 8alpha-Amino-6-n-propylergoline | HCID 13468803 | — |
Reaction Steps
12 g (ca 30 mM) of 8α-benzyloxycarbonylamino)-6-n-propylergoline obtained from step (d) and 1.5 g palladium on charcoal (10% by weight) in 500 ml ethanol are hydrogenated at normal pressure until hydrogen uptake ceases. The mixture is filtered and concentrated. This resultant heading compound is crystallised from methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04764517 |
| Source dataset | uspto-grants-1988_08 |
| ORD ID | ord-1847d07e81a74fdd8f8adb629f105173 |
| Source note | uspto-grants-1988_08 |