HCID 86595308, compound → HCID 17961982, compound

Participants

Reaction Steps

A solution of ethyl (2E)-3-(1-formyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)-2-propenoate (40 g) in a mixture of ethanol (200 ml) and tetrahydrofuran (500 ml) was treated with 10% palladium carbon (10 g) under a hydrogen atmosphere at room temperature for 4.5 hours. After the catalyst was filtered off, the filtrate was concentrated in vacuo to give ethyl 3-(1-formyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)propanoate (40.1 g). This product was used in the next step without further purification.

Provenance & Evidence