Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → Ave-9488
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| 반응물 | 2-Aminoindan hydrochloride | HCID 122764 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | Ave-9488 | HCID 10131276 | — |
반응 단계
43.70 g (258 mol) 2-aminoindane hydrochloride and 53.43 g (528 mmol) triethylamine were added to 250 ml of tetrahydrofuran, 42.89 g (270 mmol) 4-fluorobenzoylchloride were added, and the mixture was stirred for 2 h at RT.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07179839B2 |
| 출처 데이터셋 | uspto-grants-2007_02 |
| ORD ID | ord-718b7980b122441ab1ee2810010504e8 |
| 출처 메모 | uspto-grants-2007_02 |