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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 349602Generated: October 25, 2026

Carbon Dioxide → Neopeltolide

https://huagongshe.com/reaction/349602

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbon DioxideHCID 280—
ReactantGentamicinHCID 3467—
ReactantL-GlutamineHCID 5961—
Reactant4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl)amino)-(2S,5R,6R)-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate, hydrate (1:1:1)HCID 22502—
Reactant4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acidHCID 23831—
ProductNeopeltolideHCID 16115403—

Reaction Steps

All cell lines are maintained in Roswell Park Memorial Institute (RPMI) medium 1640 supplemented with 100 U/mL penicillin 100 μg/ml streptomycin, 60 μg/ml L-glutamine, 18 mM HEPES, 0.05 mg/mL gentamycin and 10% fetal bovine serum. Cell lines are cultured in plastic tissue culture flasks and kept in an incubator at 37° C. in humidified air containing 5% CO2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07179828B2
Source datasetuspto-grants-2007_02
ORD IDord-54430c6430da44529262d57f7ce4b87f
Source noteuspto-grants-2007_02