Oxalyl chloride → 2-Chloro-4,5-difluorobenzoyl Isocyanate

HRID 349728Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 349728
[Cl:1][C:2]1[CH:10]=[C:9]([F:11])[C:8]([F:12])=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].C(Cl)(=O)[C:14](Cl)=[O:15]>ClCCl>[Cl:1][C:2]1[CH:10]=[C:9]([F:11])[C:8]([F:12])=[CH:7][C:3]=1[C:4]([N:6]=[C:14]=[O:15])=[O:5]

Komponenten

4

Edukt 2

HCID 65578Oxalyl chlorideHCID 23171512-Chloro-4,5-difluorobenzamide

Produkt 1

HCID 115575832-Chloro-4,5-difluorobenzoyl Isocyanate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

2-Chloro-4,5-difluorobenzamide was dissolved in dichloromethane, admixed with 1.5 eq. of oxalyl chloride and heated to reflux for 16 hours. The reaction mixture was concentrated under high vacuum and reacted in stage b without further purification.

Aufarbeitung

  1. temperatureheated
  2. temperatureto reflux for 16 hours
  3. concentrationThe reaction mixture was concentrated under high vacuum
  4. customreacted in stage b without further purification

Quellen und Nachweise

ORD-Eintrag
ord-37b2489659b54d3c86a3d1c2a4eced91
Quelldatensatz
uspto-grants-2007_02
Patentnummer
US07179941B2

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