[1-(3,5-Dibenzyloxybenzyl)-4-phenyl-3-pyrrolyl]methanol → 1-(3,5-Dibenzyloxybenzyl)-4-phenylpyrrole-3-carbaldehyde

Participants

Reaction Steps

A mixture of [1-(3,5-dibenzyloxybenzyl)-4-phenyl-3-pyrrolyl]methanol (23.8 g), activated manganese dioxide (50.00 g), and tetrahydrofuran (200 ml) was stirred at room temperature for two hours. After the manganese dioxide was removed by filtration, the filtrate was concentrated. The colorless crystals obtained were collected by filtration to yield 1-(3,5-dibenzyloxybenzyl)-4-phenylpyrrole-3-carbaldehyde (23.10 g, yield: 97%). This was recrystallized from tetrahydrofuran-hexane. Melting point: 117–118° C.

Provenance & Evidence