HCID 23025113, compound → HCID 23024822, compound

Participants

Reaction Steps

A mixture of (1-benzyl-5-propyl-1H-pyrazol-4-yl)methanol (14.99 g), activated manganese dioxide (30.0 g) and, tetrahydrofuran (300 ml) was stirred at room temperature for 3 days. After the manganese dioxide was removed by filtration, the filtrate was concentrated. The residue was subjected to silica gel column chromatography, and 1-benzyl-5-propyl-1H-pyrazole-4-carbaldehyde (10.69 g, yield: 72%) was obtained as a colorless oily substance from the fraction eluted with ethyl acetate-hexane (1:2, volume ratio).

Provenance & Evidence