Ethanol → HCID 69421614, compound

Participants

Reaction Steps

A mixture of ethyl 3-[3-benzyloxy-1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-1H-pyrazol-4-yl]propionate (380 mg), 1 N aqueous sodium hydroxide solution (3 ml), tetrahydrofuran (3 ml), and ethanol (3 ml) was stirred at room temperature for one hour, and then diluted with 1 N hydrochloric acid (5 ml) to give colorless crystals, which were collected by filtration. This was recrystallized from ethyl acetate-hexane, to yield 3-[3-benzyloxy-1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-1H-pyrazol-4-yl]propionic acid (300 mg, yield: 83%). Melting point: 108–109° C.

Provenance & Evidence