反应详情

A mixture of N-cyano-1-methylhydrazinecarboximidothioic acid methyl ester (200 mg) and 3-(3-aminopropoxy)-N,N-dimethylbenzenemethanamine (289 mg) was heated at 40° under a reduced pressure of 20 mm of mercury for 4 hours. The reaction mixture was cooled, triturated with ether and the resulting solid recrystallised from ethyl acetate to give the title compound as colourless crystals (246 mg) m.p. 95°-96.5°.

1. temperaturewas heated at 40° under a reduced pressure of 20 mm of mercury for 4 hours
2. temperatureThe reaction mixture was cooled
3. customtriturated with ether
4. customthe resulting solid recrystallised from ethyl acetate