3-Benzyloxy-4-methoxypicolinic acid → 3-Hydroxy-4-methoxypyridine-2-carboxylic acid

Participants

Reaction Steps

3-Benzyloxy-4-methoxypicolinic acid (5.3 g) was suspended in 25 ml of ethanol. 10% palladium-carbon (0.5 g) was added to the suspension. The mixture was then catalytically hydrogenated under atmospheric pressure for 30 min. The reaction solution was filtered under the reduced pressure. The filtrate was concentrated under the reduced pressure to give 2.8 g (yield 81.6%) of the title compound as colorless powder.

Provenance & Evidence