Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Nitroaniline | HCID 7475 | — |
| Reactant | 4-Chlorobutyronitrile | HCID 12336 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 91989079 | HCID 91989079 | — |
Reaction Steps
A mixture of 40.0 g (290 mmol) of 4-nitroaniline and 40.0 ml (421 mmol) of 4-chlorobutyronitrile is heated at the boil (about 190° C.) for 30 minutes using a hot-air fan. The mixture is allowed to cool and is digested with ethyl acetate, giving 1-(4-nitrophenyl)pyrrolidin-2-ylideneamine, hydrochloride, as a brown solid, ESI 206.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07183277B2 |
|---|
| Source dataset | uspto-grants-2007_02 |
|---|
| ORD ID | ord-ecf242ec1037449f8b77fcb48eec4d07 |
|---|
| Source note | uspto-grants-2007_02 |
|---|
