Lithium iodide → HCID 68866919, compound

Participants

Reaction Steps

In 6 mL of pyridine was dissolved 313 mg of methyl 2-(octadecanoylamino)-3-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosylthio)propionate, 515 mg of lithium iodide was added to the solution and the resulting mixture was refluxed under nitrogen atmosphere for 4 hours. The reaction mixture was extracted with ethyl acetate, washed with 2 mol/L of hydrochloric acid, the ethyl acetate layer was dried over anhydrous magnesium sulfate, and then, the solvent was removed under reduced pressure. The finally obtained residue was purified by medium pressure column chromatography (Eluent; chloroform:methanol=15:1) to obtain 247 mg of 2-(octadecanoylamino)-3-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosylthio) propionic acid.

Provenance & Evidence