HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Nitrophenyl)-3-n-pentyl-3-azabicyclo[3.1.1]heptane-2,4-dione → 1-(4-Amino-phenyl)-3-pentyl-3-aza-bicyclo[3.1.1]heptane-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Nitrophenyl)-3-n-pentyl-3-azabicyclo[3.1.1]heptane-2,4-dione | HCID 14872631 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(4-Amino-phenyl)-3-pentyl-3-aza-bicyclo[3.1.1]heptane-2,4-dione | HCID 14872636 | — |
Reaction Steps
In a manner analogous to that described in Example 1, 2.58 g of 1-(4-nitrophenyl)-3-n-pentyl-3-azabicyclo[3.1.1]heptane-2,4-dione in 75 ml of ethanol are hydrogenated in the presence of 0.15 g of palladium-on-carbon and worked up. Melting point 92°-94° (from ethyl acetate/petroleum ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04764640 |
| Source dataset | uspto-grants-1988_08 |
| ORD ID | ord-8c7bb97ee5c24292acd106831ce5b555 |
| Source note | uspto-grants-1988_08 |